Synthesis, Physicochemical, Labeling and In Vivo Characterization of ⁴⁴Sc-Labeled DO3AM-NI as a Hypoxia-Sensitive PET Probe

Hypoxia promotes angiogenesis, which is crucial for tumor growth, and induces malignant progression and increases the therapeutic resistance. Positron emission tomography (PET) enables the detection of the hypoxic regions in tumors using 2-nitroimidazole-based radiopharmaceuticals. We describe here...

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Үндсэн зохиолчид:	Dániel Szücs, Tibor Csupász, Judit P. Szabó, Adrienn Kis, Barbara Gyuricza, Viktória Arató, Viktória Forgács, Adrienn Vágner, Gábor Nagy, Ildikó Garai, Dezső Szikra, Imre Tóth, György Trencsényi, Gyula Tircsó, Anikó Fekete
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2022-05-01
Цуврал:	Pharmaceuticals
Нөхцлүүд:	radiopharmaceutical physicochemical study scandium-44 radiochemistry positron emission tomography tumor hypoxia
Онлайн хандалт:	https://www.mdpi.com/1424-8247/15/6/666
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!