Therapeutic Performance Evaluation of ²¹³Bi-Labelled Aminopeptidase N (APN/CD13)-Affine NGR-Motif ([²¹³Bi]Bi-DOTAGA-cKNGRE) in Experimental Tumour Model: A Treasured Tailor for Oncology

Since NGR-tripeptides (asparagine-glycine-arginine) selectively target neoangiogenesis-associated Aminopeptidase N (APN/CD13) on cancer cells, we aimed to evaluate the in vivo tumour targeting capability of radiolabelled, NGR-containing, ANP/CD13-selective [²¹³Bi]Bi-DOTAGA-cKNGRE in CD13p...

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Autors principals:	Zita Képes, Viktória Arató, Judit P. Szabó, Barbara Gyuricza, Dániel Szücs, István Hajdu, Anikó Fekete, Frank Bruchertseifer, Dezső Szikra, György Trencsényi
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-02-01
Col·lecció:	Pharmaceutics
Matèries:	APN/CD13 (Aminopeptidase N) [<sup>213</sup>Bi]Bi-DOTAGA-cKNGRE fibrosarcoma HT1080 NGR (asparagine-glycine-arginine) positron emission tomography (PET)
Accés en línia:	https://www.mdpi.com/1999-4923/15/2/491
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