The HIV-1 Vpr R77Q mutant alters host apoptotic gene regulation in CD4+ T cells

IntroductionHIV-1 viral protein R (Vpr) is a multifunctional accessory protein that modulates host cellular pathways and contributes to viral pathogenesis. The HIV-1 Vpr R77Q polymorphism is enriched in long-term non-progressors (LTNPs) and has been associated with reduced overall cell death and a s...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Sidney T. Sithole, Joshua Ramsey, Macey C. Call, Kenneth K. K. Ewool, Brian D. Poole, Brett E. Pickett, Bradford K. Berges
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-06-01
Serija:	Frontiers in Cellular and Infection Microbiology
Teme:	AIDS apoptosis HIV host–virus interaction RNA sequencing transcriptomics
Online dostop:	https://www.frontiersin.org/articles/10.3389/fcimb.2026.1830094/full
Oznake:	Označite Brez oznak, prvi označite!