Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection
The majority of T cells encountered by HIV-1 are non-activated and do not readily allow productive infection. HIV-1 Vpr is highly abundant in progeny virions, and induces signalling and HIV-1 LTR transcription. We hence hypothesized that Vpr might be a determinant of non-activated T-cell infection....
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2016-01-01
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| coleção: | Open Biology |
| Assuntos: | |
| Acesso em linha: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160046 |
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