Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington's disease

Altered neuronal activity in the striatum appears to be a key component of Huntington's disease (HD), a fatal, neurodegenerative condition. To assess this hypothesis in freely behaving transgenic rats that model HD (tgHDs), we used chronically implanted micro-wires to record the spontaneous activity...

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Detalles Bibliográficos

Principais autores:	Benjamin R. Miller, Adam G. Walker, Stephen C. Fowler, Stephan von Hörsten, Olaf Riess, Michael A. Johnson, George V. Rebec
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2010-01-01
Series:	Neurobiology of Disease
Assuntos:	Huntington's disease Transgenic Rat Striatum Medium spiny neurons Electrophysiology
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0969996109002654
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