Proteostasis in striatal cells and selective neurodegeneration in Huntington’s disease
Selective neuronal loss is a hallmark of neurodegenerative diseases, including Huntington’s disease (HD). Although mutant huntingtin, the protein responsible for Huntington’s disease, is expressed ubiquitously, a subpopulation of neurons in the striatum is the first to succumb. In this review, we ex...
Kaydedildi:
| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2014-08-01
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| Seri Bilgileri: | Frontiers in Cellular Neuroscience |
| Konular: | |
| Online Erişim: | http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00218/full |
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