Pericellular heparan sulfate proteoglycans: Role in regulating the biosynthetic response of nucleus pulposus cells to osmotic loading

Abstract Background Daily physiologic loading causes fluctuations in hydration of the intervertebral disc (IVD); thus, the embedded cells experience cyclic alterations to their osmotic environment. These osmotic fluctuations have been described as a mechanism linking mechanics and biology, and have...

Descrición completa

Detalles Bibliográficos

Principais autores:	Carly M. Krull, Jordan Rife, Brett Klamer, Devina Purmessur, Benjamin A. Walter
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2022-06-01
Series:	JOR Spine
Assuntos:	heparan sulfate proteoglycan intervertebral disc mechanotransduction nucleus pulposus osmotic pericellular matrix
Acceso en liña:	https://doi.org/10.1002/jsp2.1209
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!