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Antitumor activity of antimicrobial peptides containing CisoDGRC in CD13 negative breast cancer cells.

BACKGROUND: isoAsp-Gly-Arg (isoDGR) is a derivative of the Asn-Gly-Arg (NGR) motif, which is used as a targeted delivery tool to aminopeptidase N (CD13) positive cells. Recent studies have shown that cyclic isoDGR (CisoDGRC) has a more efficient affinity with α(v)β(3), a type of integrin that overex...

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Xehetasun bibliografikoak
Egile Nagusiak: Lei Hou, Xinhan Zhao, Pei Wang, Qian Ning, Min Meng, Caigang Liu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2013-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3543424?pdf=render
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