Bronchial epithelial cell-derived extracellular vesicles drive inflammasome activation and NTHi infection in COPD

Extracellular vesicles (EVs) are lipid-membrane bound vesicles that can be beneficial or detrimental depending on the content they carry. As epithelial cells are the first line of defense against harmful particles, this work explored the role of bronchial epithelial cell-derived EVs (CepEVs) in the...

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Autori principali:	Georgia Bateman, Hong Guo-Parke, Caitlyn Harvey, Aoife Rodgers, Anna Krasnodembskaya, Dermot Linden, Rabindra Tirouvanziam, Lee A. Borthwick, Andrew J. Fisher, Judith Coppinger, Joe Kidney, Clifford C. Taggart
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-01-01
Serie:	Frontiers in Immunology
Soggetti:	extracellular vesicles COPD NLRP3 macrophages NTHi
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1713012/full
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