Senolytic therapy reduces inflammation in epithelial cells from COPD patients and in smoke-exposure mice

IntroductionChronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, with increased numbers of senescent cells found within the COPD Lung. Senescent cells may drive pathology by causing defective tissue repair and driving chronic inflammation via the release of inflammato...

Description complète

Détails bibliographiques

Auteurs principaux:	Jonathan R. Baker, Leah Daly, Shyreen Hassibi, Genki Kimura, Yuki Nishimoto, Yasuo Kizawa, Kazuhiro Ito
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-04-01
Collection:	Frontiers in Medicine
Sujets:	COPD senescence senolytic epithelial cells SASP inflammation
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1451056/full
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!