Targeting monopolar spindle kinase I (Mps1 or TTK) induces radiosensitization in syngeneic models of triple negative breast cancer (TNBC) and potentiates type I interferon (T1IFN) signaling

Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype that disproportionately impacts Black women and has limited effective therapeutic options. Consequently, there is an urgent need to develop novel approaches for the treatment of TNBC. Previously, we identified monopolar spin...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kassidy M. Jungles, Caroline R. Bishop, Cydnee M. Wilson, Meilan Liu, Kalli R. Jungles, Kari Wilder-Romans, Corey W. Speers, Lori J. Pierce, James M. Rae
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-08-01
Schriftenreihe:	Neoplasia: An International Journal for Oncology Research
Schlagworte:	Monopolar spindle kinase I Radiotherapy Radiosensitization Type I interferon Breast cancer
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1476558625000697
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