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Studies of Interaction Mechanism between Pyrido [3,4-<i>d</i>] Pyrimidine Inhibitors and Mps1

Monopolar spindle 1 (Mps1), a dual-specific kinase, is related to the proper execution of chromosome biorientation and mitotic checkpoint signaling. The overexpression of Mps1 promotes the occurrence of cancer or the survival of aneuploid cancer cells, in other words, the reduction of Mps1 will seve...

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Principais autores: Cheng Xing, Xiaoping Zhou, Chengjuan Chen, Wei Sun, Qingchuan Zheng, Di Liang
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2021-08-01
Serija:Molecules
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Online dostop:https://www.mdpi.com/1420-3049/26/16/5075
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