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H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis

Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure regulate meiotic recombination. Here, we identify acetylation of histone H4 at Lys44 (H4K44ac) occurring on th...

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Bibliografische Detailangaben
Hauptverfasser: Jialei Hu, Greg Donahue, Jean Dorsey, Jérôme Govin, Zuofei Yuan, Benjamin A. Garcia, Parisha P. Shah, Shelley L. Berger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015-12-01
Schriftenreihe:Cell Reports
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2211124715012590
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