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Small conductance calcium activated K+ channel inhibitor decreases stretch induced vulnerability to atrial fibrillation

Background: Atrial dilation is an important risk factor for atrial fibrillation (AF) and animal studies have found that acute atrial dilation shortens the atrial effective refractory period (AERP) and increases the risk of AF. Stretch activated ion channels (SACs) and calcium channels play a role in...

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Principais autores: Yannan Yan, Mark Alexander Skarsfeldt, Jonas Goldin Diness, Bo Hjorth Bentzen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-12-01
coleção:International Journal of Cardiology: Heart & Vasculature
Assuntos:
Ion channel
Atrial fibrillation
SK channel
KCa2
Stretch
Pharmacology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S235290672100186X
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