Activation of M1 mAChRs by lesatropane rescues glutamate neurotoxicity in PC12 cells via PKC-mediated phosphorylation of ERK1/2
Lesatropane, a synthesized chiral tropane (3S, 6S-isomer of satropane), is a novel muscarinic agonist, and is being under preclinical development in China for the treatment of primary glaucoma. The reports concerning that activation of muscarinic acetylcholine receptors (mAChRs) could protect cells...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2013-08-01
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| Serie: | Biomolecules & Biomedicine |
| Soggetti: | |
| Accesso online: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/2346 |
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