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Liquid-liquid phase separation and extracellular multivalent interactions in the tale of galectin-3

Galectin-3 consists of an unstructured N-terminal domain (NTD) and a structured carbohydrate-recognition domain and agglutinates neutrophils and glycosylated molecules in the extracellular milieu. Here the authors combine biophysical and biochemical experiments with NMR measurements and show that th...

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Autori principali: Yi-Ping Chiu, Yung-Chen Sun, De-Chen Qiu, Yu-Hao Lin, Yin-Quan Chen, Jean-Cheng Kuo, Jie-rong Huang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2020-03-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-020-15007-3
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