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A Few Charged Residues in Galectin‐3′s Folded and Disordered Regions Regulate Phase Separation

Abstract Proteins with intrinsically disordered regions (IDRs) often undergo phase separation to control their functions spatiotemporally. Changing the pH alters the protonation levels of charged sidechains, which in turn affects the attractive or repulsive force for phase separation. In a cell, the...

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Bibliografiset tiedot
Päätekijät: Yung‐Chen Sun, Tsung‐Lun Hsieh, Chia‐I Lin, Wan‐Yu Shao, Yu‐Hao Lin, Jie‐rong Huang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley 2024-11-01
Sarja:Advanced Science
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Linkit:https://doi.org/10.1002/advs.202402570
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