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Dimethyloxalylglycine Suppresses SREBP1c and Lipogenic Gene Expressions in Hepatocytes Independently of HIF1A

Dimethyloxalylglycine (DMOG) is a representative inhibitor of the prolyl hydroxylase domain (PHD), which mediates the degradation of hypoxia-inducible factor-1-alpha (HIF1A). DMOG exerts its pharmacological effects via the canonical pathway that involves PHD inhibition; however, it remains unclear w...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yong Seong Kwon, Ye Eun Cho, Yeonsoo Kim, Minseob Koh, Seonghwan Hwang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2024-03-01
Rangatū:Current Issues in Molecular Biology
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1467-3045/46/3/151
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