Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice

Wnt/β-catenin is involved in every aspect of embryonic development and in the pathogenesis of many human diseases, and is also implicated in organ fibrosis. However, the role of β-catenin-mediated signaling on liver fibrosis remains unclear. To explore this issue, the effects of PRI-724, a selective...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Yosuke Osawa, Keisuke Oboki, Jun Imamura, Ekumi Kojika, Yukiko Hayashi, Tsunekazu Hishima, Toshiji Saibara, Futoshi Shibasaki, Michinori Kohara, Kiminori Kimura
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2015-11-01
Serie:	EBioMedicine
Soggetti:	Liver Fibrosis Beta-catenin Hepatic stellate cell Macrophage***
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2352396415301742
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!