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Identification of 2′,4′-Dihydroxychalcone as an Antivirulence Agent Targeting HlyU, a Master Virulence Regulator in Vibrio vulnificus

The emergence of antimicrobial resistance and rapid acclimation allows Vibrio vulnificus to rapidly propagate in the host. This problematic pathological scenario can be circumvented by employing an antivirulence strategy, treating Vibrio infections without hindering the bacterial growth. We develope...

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Kaydedildi:
Asıl Yazarlar: Saba Imdad, Nayab Batool, Subhra Pradhan, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2018-06-01
Seri Bilgileri:Molecules
Konular:
HlyU inhibitor
virulence factors
toxin-network
Vibrio vulnificus
2′,4′-dihydroxychalcone
foodborne infectious disease
Galleria mellonella infection model, orthogonal screening reporter platform
Online Erişim:http://www.mdpi.com/1420-3049/23/6/1492
Etiketler: Etiketle
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