Identification of 2′,4′-Dihydroxychalcone as an Antivirulence Agent Targeting HlyU, a Master Virulence Regulator in Vibrio vulnificus

The emergence of antimicrobial resistance and rapid acclimation allows Vibrio vulnificus to rapidly propagate in the host. This problematic pathological scenario can be circumvented by employing an antivirulence strategy, treating Vibrio infections without hindering the bacterial growth. We develope...

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Главные авторы:	Saba Imdad, Nayab Batool, Subhra Pradhan, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2018-06-01
Серии:	Molecules
Предметы:	HlyU inhibitor virulence factors toxin-network Vibrio vulnificus 2′,4′-dihydroxychalcone foodborne infectious disease Galleria mellonella infection model, orthogonal screening reporter platform
Online-ссылка:	http://www.mdpi.com/1420-3049/23/6/1492
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