Identification of 2′,4′-Dihydroxychalcone as an Antivirulence Agent Targeting HlyU, a Master Virulence Regulator in Vibrio vulnificus

The emergence of antimicrobial resistance and rapid acclimation allows Vibrio vulnificus to rapidly propagate in the host. This problematic pathological scenario can be circumvented by employing an antivirulence strategy, treating Vibrio infections without hindering the bacterial growth. We develope...

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Автори:	Saba Imdad, Nayab Batool, Subhra Pradhan, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2018-06-01
Серія:	Molecules
Предмети:	HlyU inhibitor virulence factors toxin-network Vibrio vulnificus 2′,4′-dihydroxychalcone foodborne infectious disease Galleria mellonella infection model, orthogonal screening reporter platform
Онлайн доступ:	http://www.mdpi.com/1420-3049/23/6/1492
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