Increased CpG methylation at the CDH1 locus in inflamed ileal mucosa of patients with Crohn disease
Abstract Background E-cadherin, a major actor of cell adhesion in the intestinal barrier, is encoded by the CDH1 gene associated with susceptibility to Crohn Disease (CD) and colorectal cancer. Since epigenetic mechanisms are suspected to contribute to the multifactorial pathogenesis of CD, we studi...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2024-02-01
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| Serie: | Clinical Epigenetics |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13148-024-01631-z |
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