CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci

Abstract Chronic hyperglycemia is a major risk factor for glomerular or retinal microangiopathy and cardiovascular complications of type 1 diabetes (T1D). At the interface of genetics and environment, dynamic epigenetic changes associated with hyperglycemia may unravel some of the mechanisms contrib...

Description complète

Détails bibliographiques

Auteurs principaux:	Xiaojian Shao, Sophie Le Fur, Warren Cheung, Marie-Pierre Belot, Kevin Perge, Natacha Bouhours-Nouet, Candace Bensignor, Lucie Levaillant, Bing Ge, Tony Kwan, Mark Lathrop, Tomi Pastinen, Pierre Bougnères
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2025-05-01
Collection:	Scientific Reports
Sujets:	CpG methylation Hyperglycemia Type 1 diabetes complications Angiogenesis
Accès en ligne:	https://doi.org/10.1038/s41598-024-82698-9
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!