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Citrullinated α-enolase is an effective target for anti-cancer immunity

Targeting post-translationally modified epitopes may provide a new strategy for generating tumor specific immune responses. Citrullination is the post-translational modification of arginine to citrulline catalyzed by peptidylarginine deaminase (PAD) enzymes. Presentation of citrullinated peptides on...

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Principais autores: Katherine Cook, Ian Daniels, Peter Symonds, Tracy Pitt, Mohamed Gijon, Wei Xue, Rachael Metheringham, Lindy Durrant, Victoria Brentville
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2018-02-01
Serier:OncoImmunology
Fag:
enolase
citrullination
cancer
tumor immunotherapy
cd4 t cells
autophagy
mhc-ii
Online adgang:http://dx.doi.org/10.1080/2162402X.2017.1390642
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