Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)

ABSTRACT The necessity for intravenous administration of remdesivir confines its utility for treatment of coronavirus disease 2019 (COVID-19) to hospitalized patients. We evaluated the broad-spectrum antiviral activity of ODBG-P-RVn, an orally available, lipid-modified monophosphate prodrug of the r...

詳細記述

書誌詳細

主要な著者:	Michael K. Lo, Punya Shrivastava-Ranjan, Payel Chatterjee, Mike Flint, James R. Beadle, Nadejda Valiaeva, Joyce Murphy, Robert T. Schooley, Karl Y. Hostetler, Joel M. Montgomery, Christina F. Spiropoulou
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology 2021-12-01
シリーズ:	Microbiology Spectrum
主題:	SARS-CoV-2 Ebola virus Nipah virus respiratory viruses hemorrhagic fever virus filovirus
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/Spectrum.01537-21
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!