QR Code

Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats

Summary: Background: Remdesivir was the first prodrug approved to treat coronavirus disease 2019 (COVID-19) and has the potential to be used during pregnancy. However, it is not known whether remdesivir and its main metabolite, GS-441524 have the potential to cross the blood-placental barrier. We h...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ling Yang, I-Hsin Lin, Lie-Chwen Lin, Jeffrey W. Dalley, Tung-Hu Tsai
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2022-07-01
Rangatū:EBioMedicine
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2352396422002766
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!