Protein neddylation in lung tumorigenesis: Target validation and targeted therapy
Much akin to ubiquitylation, neddylation is catalyzed by a cascade of three enzymes: E1 NEDD8-activating enzyme, E2 NEDD8-conjugating enzyme (UBE2M or UBE2F), and E3 NEDD8 ligases. The best-known neddylation substrates are the members of cullin family, leading to the activation of Cullin-RING ligase...
Kaydedildi:
| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
KeAi Communications Co. Ltd.
2025-09-01
|
| Seri Bilgileri: | Fundamental Research |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2667325823002856 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|