3174 Tumor suppressors p53 and ARF control oncogenic potential of triple-negative breast cancer cells by regulating RNA editing enzyme ADAR1

OBJECTIVES/SPECIFIC AIMS: Triple-negative breast cancer (TNBC) accounts for one-fifth of the breast cancer patient population. The heterogeneous nature of TNBC and lack of options for targeted therapy make its treatment a constant challenge. The co-deficiency of tumor suppressors p53 and ARF is a si...

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Hlavní autoři:	Che-Pei Kung, Emily Bross, Emily Bramel, Eric Freeman, Thwisha Sabloak, Catherine Kuzmicki, Mike Benjamin, Leonard Maggi, Jason Weber
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cambridge University Press 2019-03-01
Edice:	Journal of Clinical and Translational Science
On-line přístup:	https://www.cambridge.org/core/product/identifier/S205986611900061X/type/journal_article
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!