The WASH-complex subunit Strumpellin regulates integrin αIIbβ3 trafficking in murine platelets
Abstract The platelet specific integrin αIIbβ3 mediates platelet adhesion, aggregation and plays a central role in thrombosis and hemostasis. In resting platelets, αIIbβ3 is expressed on the membrane surface and in intracellular compartments. Upon activation, the number of surface-expressed αIIbβ3 i...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2023-06-01
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| Seria: | Scientific Reports |
| Dostęp online: | https://doi.org/10.1038/s41598-023-36387-8 |
| Etykiety: |
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