The WASH-complex subunit Strumpellin regulates integrin αIIbβ3 trafficking in murine platelets
Abstract The platelet specific integrin αIIbβ3 mediates platelet adhesion, aggregation and plays a central role in thrombosis and hemostasis. In resting platelets, αIIbβ3 is expressed on the membrane surface and in intracellular compartments. Upon activation, the number of surface-expressed αIIbβ3 i...
Gardado en:
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2023-06-01
|
| Series: | Scientific Reports |
| Acceso en liña: | https://doi.org/10.1038/s41598-023-36387-8 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|