A statistical measure for the skewness of X chromosome inactivation based on family trios
Abstract Background X chromosome inactivation (XCI) is an important gene regulation mechanism in females to equalize the expression levels of X chromosome between two sexes. Generally, one of two X chromosomes in females is randomly chosen to be inactivated. Nonrandom XCI (XCI skewing) is also obser...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2018-12-01
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| Collection: | BMC Genetics |
| Sujets: | |
| Accès en ligne: | http://link.springer.com/article/10.1186/s12863-018-0694-8 |
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