BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

Abstract Background X chromosome inactivation (XCI) is an epigenetic phenomenon that one of two X chromosomes in females is transcriptionally silenced during early embryonic development. Skewed XCI has been reported to be associated with some X-linked diseases. There have been several methods measur...

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Detalhes bibliográficos

Principais autores:	Wen-Yi Yu, Yu Zhang, Meng-Kai Li, Zi-Ying Yang, Wing Kam Fung, Pei-Zhen Zhao, Ji-Yuan Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-05-01
coleção:	BMC Bioinformatics
Assuntos:	Skewed X chromosome inactivation Bayesian method Penalized Fieller’s method Graves’ disease data Minnesota Center for Twin and Family Research data
Acesso em linha:	https://doi.org/10.1186/s12859-022-04721-y
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