BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

Abstract Background X chromosome inactivation (XCI) is an epigenetic phenomenon that one of two X chromosomes in females is transcriptionally silenced during early embryonic development. Skewed XCI has been reported to be associated with some X-linked diseases. There have been several methods measur...

Description complète

Détails bibliographiques

Auteurs principaux:	Wen-Yi Yu, Yu Zhang, Meng-Kai Li, Zi-Ying Yang, Wing Kam Fung, Pei-Zhen Zhao, Ji-Yuan Zhou
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2022-05-01
Collection:	BMC Bioinformatics
Sujets:	Skewed X chromosome inactivation Bayesian method Penalized Fieller’s method Graves’ disease data Minnesota Center for Twin and Family Research data
Accès en ligne:	https://doi.org/10.1186/s12859-022-04721-y
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!