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A statistical measure for the skewness of X chromosome inactivation based on family trios

Abstract Background X chromosome inactivation (XCI) is an important gene regulation mechanism in females to equalize the expression levels of X chromosome between two sexes. Generally, one of two X chromosomes in females is randomly chosen to be inactivated. Nonrandom XCI (XCI skewing) is also obser...

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Váldodahkkit: Si-Qi Xu, Yu Zhang, Peng Wang, Wei Liu, Xian-Bo Wu, Ji-Yuan Zhou
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2018-12-01
Ráidu:BMC Genetics
Fáttát:
Liŋkkat:http://link.springer.com/article/10.1186/s12863-018-0694-8
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