ATP and luciferase assays to determine the rate of drug action in <it>in vitro</it> cultures of <it>Plasmodium falciparum</it>

<p>Abstract</p> <p>Background</p> <p>Knowledge of the rate of action of compounds against cultured malaria parasites is required to determine the optimal time-points for drug mode of action studies, as well as to predict likely <it>in vivo</it> parasite clearance rates in order to select optimal hit...

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Autores principales:	Khan Tasmiyah, van Brummelen Anna C, Parkinson Christopher J, Hoppe Heinrich C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2012-11-01
Colección:	Malaria Journal
Materias:	<it>Plasmodium</it> ATP Luciferase Chloroquine Mefloquine Artemisinin Ritonavir Gramicidin Proteasome DFMO
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