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ATP and luciferase assays to determine the rate of drug action in <it>in vitro</it> cultures of <it>Plasmodium falciparum</it>

<p>Abstract</p> <p>Background</p> <p>Knowledge of the rate of action of compounds against cultured malaria parasites is required to determine the optimal time-points for drug mode of action studies, as well as to predict likely <it>in vivo</it> parasite clearance rates in order to select optimal hit...

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Autori principali: Khan Tasmiyah, van Brummelen Anna C, Parkinson Christopher J, Hoppe Heinrich C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-11-01
Serie:Malaria Journal
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