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Microglia Diversity in Health and Multiple Sclerosis

Multiple Sclerosis (MS) is a neurodegenerative disease characterized by multiple focal lesions, ongoing demyelination and, for most people, a lack of remyelination. MS lesions are enriched with monocyte-derived macrophages and brain-resident microglia that, together, are likely responsible for much...

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Principais autores: Sameera Zia, Khalil S. Rawji, Nathan J. Michaels, Mena Burr, Bradley J. Kerr, Luke M. Healy, Jason R. Plemel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-11-01
coleção:Frontiers in Immunology
Assuntos:
microglia
macrophages
single-cell analysis
single-cell RNA sequencing
multiple sclerosis
remyelination
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2020.588021/full
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