High‐affinity interactions and signal transduction between Aβ oligomers and TREM2
Abstract Rare coding variants in the triggering receptor expressed on myeloid cells 2 (TREM2) are associated with increased risk for Alzheimer's disease (AD), but how they confer this risk remains uncertain. We assessed binding of TREM2, AD‐associated TREM2 variants to various forms of Aβ and APOE i...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Nature
2018-10-01
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| Seri Bilgileri: | EMBO Molecular Medicine |
| Konular: | |
| Online Erişim: | https://doi.org/10.15252/emmm.201809027 |
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