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Cognitive dysfunction in type 1 diabetes: role of TREM2 in microglial activation and Aβ pathology

Abstract Background Cognitive dysfunction associated with type 1 diabetes (T1D) is closely linked to the accumulation of amyloid-beta (Aβ) oligomers. However, the role of microglia and their underlying molecular mechanisms in this process remain unclear. Triggering receptor expressed on myeloid cell...

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Bibliografische Detailangaben
Hauptverfasser: Yue Wang, Ruyue Wang, Yimeng Liu, Zhaohui Wang, Hongyan Ding, Xinyi Wei, Aikeda Aihemaitijiang, Minghan Sun, Li Zhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-01-01
Schriftenreihe:Journal of Neuroinflammation
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Online-Zugang:https://doi.org/10.1186/s12974-025-03611-3
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