Features of the 8-oxo-7,8-dihydro-2′-dGTP behavior in active site of human DNA polymerase β: structural investigation in silico
The oxidized bases in the composition of DNA as well as DNA precursors (desoxynucleotide triphosphates, dNTPs) appearing in living cell as a result of oxidative stress are the one of major sources of genomic instability. Among oxidized forms of nitrogenous bases, the 8-oxo-7,8-dihydro-2-deoxyguanine...
Guardat en:
| Autor principal: | |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Львівський національний університет імені Івана Франка
2014-04-01
|
| Col·lecció: | Біологічні студії |
| Matèries: | |
| Accés en línia: | http://publications.lnu.edu.ua/journals/index.php/biology/article/view/151 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|