Features of the 8-oxo-7,8-dihydro-2′-dGTP behavior in active site of human DNA polymerase β: structural investigation in silico
The oxidized bases in the composition of DNA as well as DNA precursors (desoxynucleotide triphosphates, dNTPs) appearing in living cell as a result of oxidative stress are the one of major sources of genomic instability. Among oxidized forms of nitrogenous bases, the 8-oxo-7,8-dihydro-2-deoxyguanine...
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| Format: | Artigo |
| Langue: | Inglês |
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Львівський національний університет імені Івана Франка
2014-04-01
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| Collection: | Біологічні студії |
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| Accès en ligne: | http://publications.lnu.edu.ua/journals/index.php/biology/article/view/151 |
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