Inhibition of Galectin-3 by ADSC-derived exosomes after cavernous nerve injury ameliorates erectile dysfunction by modulating oxidative stress and inflammatory profibrotic cascades

Abstract Background Cavernous nerve injury (CNI) is a prominent etiological factor in the development of erectile dysfunction (ED). Nevertheless, the underlying pathophysiological mechanisms of CNI-induced ED (CNI-ED) are not fully elucidated. Galectin-3 (Gal-3), an indicator of inflammation and fib...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Ruiyu Li, Guanbo Wang, Chen Feng, Tongxiang Diao, Shuai Liu, Qiang Fu
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2025-11-01
श्रृंखला:	Stem Cell Research & Therapy
विषय:	Erectile dysfunction Galectin-3 Adipose mesenchymal stem cell-derived exosomes Inflammatory profibrotic cascades Oxidative stress
ऑनलाइन पहुंच:	https://doi.org/10.1186/s13287-025-04749-w
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