Inhibition of Galectin-3 by ADSC-derived exosomes after cavernous nerve injury ameliorates erectile dysfunction by modulating oxidative stress and inflammatory profibrotic cascades

Abstract Background Cavernous nerve injury (CNI) is a prominent etiological factor in the development of erectile dysfunction (ED). Nevertheless, the underlying pathophysiological mechanisms of CNI-induced ED (CNI-ED) are not fully elucidated. Galectin-3 (Gal-3), an indicator of inflammation and fib...

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Detalhes bibliográficos

Principais autores:	Ruiyu Li, Guanbo Wang, Chen Feng, Tongxiang Diao, Shuai Liu, Qiang Fu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-11-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Erectile dysfunction Galectin-3 Adipose mesenchymal stem cell-derived exosomes Inflammatory profibrotic cascades Oxidative stress
Acesso em linha:	https://doi.org/10.1186/s13287-025-04749-w
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