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HHIP Overexpression Suppresses Human Gastric Cancer Progression and Metastasis by Reducing Its CpG Island Methylation

Human hedgehog-interacting protein (HHIP), a negative regulator of hedgehog (HH) signaling pathway, has been reported to be dysregulated in many types of cancer, including gastric cancer. However, the inhibitory role of HHIP as well as the underlying molecular mechanism of HHIP regulation in gastric...

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Principais autores: Yu Song, Jianchen Tu, Yanan Cheng, Fang Zhou, Peilin Liu, Shuangshuang Zhou, Yongjun Gu, Yang Sun
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020-12-01
סדרה:Frontiers in Oncology
נושאים:
HHIP
hedgehog signaling
gastric cancer
methylation
metastasis
growth
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fonc.2020.01667/full
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