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HHIP Overexpression Suppresses Human Gastric Cancer Progression and Metastasis by Reducing Its CpG Island Methylation

Human hedgehog-interacting protein (HHIP), a negative regulator of hedgehog (HH) signaling pathway, has been reported to be dysregulated in many types of cancer, including gastric cancer. However, the inhibitory role of HHIP as well as the underlying molecular mechanism of HHIP regulation in gastric...

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Auteurs principaux: Yu Song, Jianchen Tu, Yanan Cheng, Fang Zhou, Peilin Liu, Shuangshuang Zhou, Yongjun Gu, Yang Sun
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-12-01
Collection:Frontiers in Oncology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fonc.2020.01667/full
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