Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Abstract Alzheimer’s disease (AD) is characterized by the appearance of amyloid‐β plaques, neurofibrillary tangles, and inflammation in brain regions involved in memory. Using mass spectrometry, we have quantified the phosphoproteome of the CK‐p25, 5XFAD, and Tau P301S mouse models of neurodegenerat...

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Auteurs principaux:	Nader Morshed, William T Ralvenius, Alexi Nott, L Ashley Watson, Felicia H Rodriguez, Leyla A Akay, Brian A Joughin, Ping‐Chieh Pao, Jay Penney, Lauren LaRocque, Diego Mastroeni, Li‐Huei Tsai, Forest M White
Format:	Artigo
Langue:	Inglês
Publié:	Springer Nature 2020-12-01
Collection:	Molecular Systems Biology
Sujets:	Alzheimer's disease microglia phosphoproteomics Siglec‐8 Siglec‐F
Accès en ligne:	https://doi.org/10.15252/msb.20209819
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