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Therapeutic potential to target sialylation and SIGLECs in neurodegenerative and psychiatric diseases

Sialic acids, commonly found as the terminal carbohydrate on the glycocalyx of mammalian cells, are pivotal checkpoint inhibitors of the innate immune system, particularly within the central nervous system (CNS). Sialic acid-binding immunoglobulin-like lectins (SIGLECs) expressed on microglia are ke...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jannis Wißfeld, Tawfik Abou Assale, German Cuevas-Rios, Huan Liao, Harald Neumann
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Frontiers Media S.A. 2024-03-01
Цуврал:Frontiers in Neurology
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/articles/10.3389/fneur.2024.1330874/full
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