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Therapeutic potential to target sialylation and SIGLECs in neurodegenerative and psychiatric diseases

Sialic acids, commonly found as the terminal carbohydrate on the glycocalyx of mammalian cells, are pivotal checkpoint inhibitors of the innate immune system, particularly within the central nervous system (CNS). Sialic acid-binding immunoglobulin-like lectins (SIGLECs) expressed on microglia are ke...

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Detaylı Bibliyografya
Asıl Yazarlar: Jannis Wißfeld, Tawfik Abou Assale, German Cuevas-Rios, Huan Liao, Harald Neumann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2024-03-01
Seri Bilgileri:Frontiers in Neurology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fneur.2024.1330874/full
Etiketler: Etiketle
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