TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments
The RNA binding protein TRBP is a component of the Dicer complex but its role in microRNA biogenesis remains poorly understood. Here the authors use a crowded RNA environment and single-molecule imaging to show that TRBP acts as a gatekeeper to prevent Dicer engagement with pre miRNA-like substrates...
Na minha lista:
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2016-12-01
|
| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/ncomms13694 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|